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Prostate cancer is one of the most common cancers diagnosed in men worldwide[1]. Early and accurate diagnosis is critical for determining the best treatment approach. While prostate-specific antigen (PSA) blood tests and digital rectal exams can suggest the presence of prostate cancer, the only definitive way to diagnose prostate cancer is through a prostate biopsy[13].

A prostate biopsy involves using a needle to take small samples of tissue from the prostate gland. A pathologist then examines the tissue under a microscope to check for cancer cells. Traditionally, prostate biopsies have been done using a transrectal approach, where the biopsy needle is inserted through the wall of the rectum. However, this approach has limitations and risks.

The transperineal fusion biopsy approach has emerged as a superior alternative in recent years. With this technique, the biopsy needle is inserted through the perineum (the area of skin between the scrotum and anus) and into the prostate. MRI images of the prostate are fused with real-time ultrasound to guide the needle to suspicious areas.